Marseille Pure Element Hair Product Reviving Shampoo & Conditioner
After extensive R&D, Marseille Pure Element Hair Product has finally made revolutionary hair regrowth shampoos & conditioners with more natural ingredients and effective hair regrowth factors.
Marseille Pure Element Reviving shampoo and conditioner deliver great result for both men and women with hair thinning problems. Our appropriate ingredients like Stimucap® and copper peptides have been used in the medical field / regenerative science.
The proprietary ingredients stop DHT, stimulate the scalp and urge new hair born in the follicle.
Copper Peptides stimulates hair follicles and urges new hair grow!
Copper Peptide is a well-known ingredient in the field of regenerative medicine, and it is believed to rejuvenate cells.
Here are some of the characteristics of copper peptides:
*Copper Peptides block DHT in the scalp.
(DHT is the #1 reason of hair thinning. This is important to block)
*Copper Peptides stimulate blood flow to the scalp and increase hair follicle size.
(It delivers oxygen and nutrients and makes thicker follicles)
Stimucap® protects the hair follicle and nourishes the bulb, improving hair health and appearance.
Stimucap® is a breakthrough ingredient for thinning hair and controlling hair loss (Hair fortifying and revitalizing active, efficient regulator of the physiological hair growth process). Stimucap® is made of synergistic active components aimed to restore the optimal hair follicle conditions and avoid its regression, typical of the hair fibrosis.
The mechanism of action relies in the prevention of the miniaturization of the hair follicle given by the CLA Glutathione and the proliferative and regenerative action that Sodium DNA performs on the bulb germ cells.
Stimucap® protects the hair follicle and nourishes the bulb, improving hair health and appearance (volume and moisture).
(Stimucap® is developed by the Italian bioscience company, Kalichem srl).
More organic & natural ingredients
Marseille Pure Element Reviving shampoos and conditioners use 70 % organic ingredients. The ingredients like Biotin, Chamomile, Saw Palmetto and Niacin work for optimal hair health.
Saw Palmetto boosts cellular regeneration and extends the life cycle of the hair. It also calms / stops hair-loss hormones.
Biotin stimulates keratin production in hair and can increase the rate of follicle growth. Biotin supports & strengthen the hair and add shine to it. Biotin also helps in preventing various health problems like hair loss, dandruff, scalp itchiness, etc.
Niacin, commonly referred to as vitamin B3 and nicotinic acid, is an organic compound and an essential human nutrient. It improves blood circulation in the scalp and provide vital support to your hair follicles.
Chamomile helps to restore the damaged hair follicles. It helps to boost collagen production, which helps in the growth of hair. It also increases the elasticity of your hair, thus preventing hair breakage.
A new and potent metabolic agent, regulator physiological hair loss processes.
Clinically proven ingredients
Hair growth Effect proven
Stimucap is an innovative cosmetic ingredient, formed by the balanced association for two functional compounds: CLA Glutathione and Sodium DNA. The uniqueness of this blend is based on the complementary actions of two active substances.
1) The molecule of CLA Glutathione, which derives from the coupling of one molecule of Coujugated Linoleic Acid (CLA), a substance already showing an intrinsic biologic activity, with the tri-peptide Glutathione in its reduced from (GSH), partially neutralised with patossium ion that is similarly provided of an intrinsic biochemical activity (Fig 1).
2) sodium DNA: Is the INCI name of an active solution of nucleotide fragments which have been purified, depolymerised and finally neutralized with sodium ions.
Hair Loss and Baldness
The time evolution of alopecia, the scalp affection generally known as baldness, is characterised by a cascade of irreversible phenomena. Firstly, a progressive involution and miniaturization of the hair follicle is observed.
Then, the follicle shifts from the sub-cutaneous layer to the dermal superficial layers, giving rise to smaller and thinner hair shafts. Successively, a fibrosis of the connective tissue around the bulb takes place. This is frequently accompanied by inflammatory progress. After the onset of these modifications to the hair follicle and the surrounding tissues, hair loss and an irreversible atrophy of the bulb occur.
Stimucap has demonstrated to be highly effective in the prevention and reduction of premature hair loss, accourding the reported experimental protocol.
Before and after the application of Stimucap lotion
Transport into cells and activity mechanism
In CLA Glutathoine, the by-polar nature given by association of the linoleic chain, which is highly lipophile, with the very hydrophilic amino-acid moiety, is responsible for the peculiar characteristics of biologic mobility of the compound. A very high bio-availability is thus derived, which is far superior to those of CLA and Glutathione when considered individually. One can logically surmise that CLA Glutathione performs its maximum activity well before the biological breakdown into its two components takes place. At the scalp level, the anti free radicals activity of GSH may counteract the degeneration of connective tissue around the bulbs, while linoleic acid acts on the inflammatory process.
Indeed, the input of CLA into the cells activates the arachidonic acid cycle, thus leading into the prostaglandinns' synthesis. These are extremely powerful molecules that act as mediators of the local inflammatory process.
Arachidonic acid, of which CLA is a precursor, requires oxygen and an electron donor in order to transform into prostaglandins. The latter activity may be guaranteed by GSH. In this case, it is readily available at the same action site as CLA, to which it is chemically bound, while it does not cross the epidermal barrier, when alone, for its hydrophilic nature. The explanation of the extraordianry activity of CLA Glutathione is based on such a mechanism (Fig 2). Indeed, recent experimental evidence shows that CLA can induce an increase in the synthesis of intracellular GSH: a real sequence of self-feeding and self-boosting actions.
The functional mechanism of the molecules of Stimucap and the synergic activity they perform, make this product adequate for the treatment of degenerative diseases of the scalp, such as alopecia.
Efficacy Evaluations of stimucap
A series of instrumental and objective evaluations have been carried out on 30 volunteers, suffering from alopecia ad telogen effuvium, in order to experimentally determine the anti-hair loss potential of Stimucap.
The "hair resistance to traction" test (pull test) results, following 3 month use by volunteers, demonstrate that Stimucap based lotion increases by 40.0% the hair fibres' resistance, while Control lotion shows a non significant, more modest increase, equal to 17.6% (Fig 4).
Subjects under testing also expressed their personal opinions about efficacy, tolerability ad pleasantness of the treatment, thus giving a sensory response concerning the perceivable parameters (Fig 5).
A statistically significant increase in the subjective tolerability and in the perceived efficacy was detected after 2 and after 3 months of treatment with the Stimucap lotion. the tested products resulted as being well tolerated and neither had negative effects, nor induced any irritation of the scalp.
By dermatological objective evaluation, the global tolerability of the product and the onset and/or intensity of possible adverse local reactions, such as dandruff and sebhorrea have also been tested. In all cases, Stimucap resulted to be very well tolerated and accepted.
The standard "wash test" also demonstrates that, after daily application to the scalp for 3 months, the Stimucap-based hair lotion can reduce hair loss. This effect takes place by a faster action when compared with the bench-mark active, the well known Control (Fig 6).